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Myod1tm1Glh
Targeted Allele Detail
Nomenclature
Symbol: Myod1tm1Glh
Name: myogenic differentiation 1; targeted mutation 1, David J Goldhamer
MGI ID: MGI:3027182
Synonyms: CEneo
Gene: Myod1  Location: Chr7:46376474-46379099 bp, + strand  Genetic Position: Chr7, 30.03 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:87370
Parent Cell Line:  GS1 (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe core enhancer, located approximately 20 kb upstream of the start of transcription, was replaced with a floxed neomycin selection cassette inserted by homologous recombination. Transcript levels in homozygous embryos and adults were determined to be less than 20% those of wild-type. (J:87370)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myod1 Mutation:  9 strains or lines available
References
Original:  J:87370 Chen JC, et al., The core enhancer is essential for proper timing of MyoD activation in limb buds and branchial arches. Dev Biol. 2004 Jan 15;265(2):502-12
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory