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Targeted Allele Detail
Symbol: Cntnap1tm1Pele
Name: contactin associated protein-like 1; targeted mutation 1, Elior Peles
MGI ID: MGI:3026869
Synonyms: Caspr-
Gene: Cntnap1  Location: Chr11:101170523-101190724 bp, + strand  Genetic Position: Chr11, 64.33 cM, cytoband D
Germline Transmission:  Earliest citation of germline transmission: J:87070
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsExon 1 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected in homozygous mutant mice by Western blot analysis of brain, spinal cord, and sciatic nerve samples. (J:87070)
View phenotypes for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cntnap1 Mutation:  25 strains or lines available
Original:  J:87070 Gollan L, et al., Caspr regulates the processing of contactin and inhibits its binding to neurofascin. J Cell Biol. 2003 Dec 22;163(6):1213-8
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.04
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