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Targeted Allele Detail
Symbol: Scgb1a1tm1Brst
Name: secretoglobin, family 1A, member 1 (uteroglobin); targeted mutation 1, Barry R Stripp
MGI ID: MGI:2684333
Synonyms: CCSP -
Gene: Scgb1a1  Location: Chr19:9061006-9065320 bp, - strand  Genetic Position: Chr19, 6.05 cM, cytoband A
Germline Transmission:  Earliest citation of germline transmission: J:86895
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
Mutation detailsA PGK-neomycin gene was inserted in exon 1 near the 3' end. This results in a truncated protein product. mRNA transcripts were lacking in homozygotes and the absence of protein was confirmed immunologically. (J:86895)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scgb1a1 Mutation:  23 strains or lines available
Original:  J:86895 Stripp BR, et al., Clara cell secretory protein: a determinant of PCB bioaccumulation in mammals. Am J Physiol. 1996 Oct;271(4 Pt 1):L656-64
All:  15 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory