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Scgb1a1tm1Brst
Targeted Allele Detail
Nomenclature
Symbol: Scgb1a1tm1Brst
Name: secretoglobin, family 1A, member 1 (uteroglobin); targeted mutation 1, Barry R Stripp
MGI ID: MGI:2684333
Synonyms: CCSP -
Gene: Scgb1a1  Location: Chr19:9083636-9087958 bp, - strand  Genetic Position: Chr19, 6.05 cM, cytoband A
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86895
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA PGK-neomycin gene was inserted in exon 1 near the 3' end. This results in a truncated protein product. mRNA transcripts were lacking in homozygotes and the absence of protein was confirmed immunologically. (J:86895)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Scgb1a1 Mutation:  17 strains or lines available
References
Original:  J:86895 Stripp BR, et al., Clara cell secretory protein: a determinant of PCB bioaccumulation in mammals. Am J Physiol. 1996 Oct;271(4 Pt 1):L656-64
All:  14 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/12/2017
MGI 6.10
The Jackson Laboratory