Tg(Pdx1-cre/Esr1*)35.6Dam
Transgene Detail
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Symbol: |
Tg(Pdx1-cre/Esr1*)35.6Dam |
Name: |
transgene insertion 35.6, Douglas A Melton |
MGI ID: |
MGI:2684319 |
Synonyms: |
Tg(Ipf1-cre/Esr1)35.6Dam, Tg(Pdx1-cre/Esr1)35.6Dam |
Transgene: |
Tg(Pdx1-cre/Esr1*)35.6Dam Location: unknown
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Alliance: |
Tg(Pdx1-cre/Esr1*)35.6Dam page
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Pdx1-cre/Esr1*)35.6Dam expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Pdx1 |
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Mutation details: The sequence encoding a tamoxifen-inducible form of a cre recombinase/estrogen receptor fusion protein was adjoined to the Ipf1 promoter to drive mosaic expression of cre recombinase in endocrine, exocrine, and duct tissue of the pancreas.
(J:76095)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Pdx1
(species not specified)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:76095 Gu G, et al., Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development. 2002 May;129(10):2447-57 |
All: |
3 reference(s) |
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