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St14tm2Bug
Targeted Allele Detail
Nomenclature
Symbol: St14tm2Bug
Name: suppression of tumorigenicity 14 (colon carcinoma); targeted mutation 2, Thomas H Bugge
MGI ID: MGI:2683723
Gene: St14  Location: Chr9:31089402-31131853 bp, - strand  Genetic Position: Chr9, 16.61 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86715
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 2 was replaced with a neomycin selection cassette. (J:86715)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 15 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any St14 Mutation:  34 strains or lines available
References
Original:  J:86715 List K, et al., Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1. J Cell Biol. 2003 Nov 24;163(4):901-10
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory