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Nbntm1Zqw
Targeted Allele Detail
Nomenclature
Symbol: Nbntm1Zqw
Name: nibrin; targeted mutation 1, Zhao-Qi Wang
MGI ID: MGI:2682000
Synonyms: Nbn-, Nbnins-6
Gene: Nbn  Location: Chr4:15957925-15992589 bp, + strand  Genetic Position: Chr4, 6.66 cM, cytoband A
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86563
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 6 was disrupted by the insertion of a neomycin selection cassette. (J:86563)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nbn Mutation:  38 strains or lines available
References
Original:  J:86563 Dumon-Jones V, et al., Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis. Cancer Res. 2003 Nov 1;63(21):7263-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/15/2018
MGI 6.12
The Jackson Laboratory