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Nbntm1Zqw
Targeted Allele Detail
Summary
Symbol: Nbntm1Zqw
Name: nibrin; targeted mutation 1, Zhao-Qi Wang
MGI ID: MGI:2682000
Synonyms: Nbn-, Nbnins-6
Gene: Nbn  Location: Chr4:15957925-15992589 bp, + strand  Genetic Position: Chr4, 6.66 cM, cytoband A
Alliance: Nbntm1Zqw page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86563
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    Exon 6 was disrupted by the insertion of a neomycin selection cassette. (J:86563)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Nbntm1Zqw
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nbn Mutation:  59 strains or lines available
References
Original:  J:86563 Dumon-Jones V, et al., Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis. Cancer Res. 2003 Nov 1;63(21):7263-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory