About   Help   FAQ
Tas1r2tm1Csz
Targeted Allele Detail
Nomenclature
Symbol: Tas1r2tm1Csz
Name: taste receptor, type 1, member 2; targeted mutation 1, Charles S Zuker
MGI ID: MGI:2681886
Synonyms: T1R2-
Gene: Tas1r2  Location: Chr4:139653538-139670280 bp, + strand  Genetic Position: Chr4, 70.82 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:86474
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 5 and 6 were replaced with a PGK-neo cassette inserted by homologous recombination. Protein was undetected by in situ hybridization of homozygous mutant taste bud sections. (J:86474)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tas1r2 Mutation:  23 strains or lines available
Notes
Results reported in J:86474 were in conjunction with a Tas1r3Sac-b "taster" allele, however qualitatively similar data was obtained in conjunction with a Tas1r3sac-d "non-taster" allele.
References
Original:  J:86474 Zhao GQ, et al., The receptors for mammalian sweet and umami taste. Cell. 2003 Oct 31;115(3):255-66
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/11/2017
MGI 6.10
The Jackson Laboratory