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Rargtm1Blt
Targeted Allele Detail
Nomenclature
Symbol: Rargtm1Blt
Name: retinoic acid receptor, gamma; targeted mutation 1, Horst Bluethmann
MGI ID: MGI:2681395
Gene: Rarg  Location: Chr15:102234938-102257517 bp, - strand  Genetic Position: Chr15, 57.4 cM, cytoband E-F3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:27473
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin selection cassette was inserted into exon 8, which encodes the B-domain. RT-PCR and northern blot analysis confirmed that no functional transcript was expressed from this allele. (J:27473)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rarg Mutation:  156 strains or lines available
References
Original:  J:27473 Look J, et al., Marked resistance of RAR gamma-deficient mice to the toxic effects of retinoic acid. Am J Physiol. 1995 Jul;269(1 Pt 1):E91-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory