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Tg(Camk2a-cre)2834Lusc
Transgene Detail
Nomenclature
Symbol: Tg(Camk2a-cre)2834Lusc
Name: transgene insertion 2834, Bernhard Luscher
MGI ID: MGI:2680625
Synonyms: CaMKIICre2834, (CaMKII)Cre2834
Transgene: Tg(Camk2a-cre)2834Lusc  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsSequence encoding cre recombinase was adjoined to 8.5 kb of the Camk2a promoter. Cre expressionr was observed in the hippocampus beginning at postnatal day 17. Expression levels gradually increased through postnatal day 34 and the expression pattern expanded to include other forebrain regions. Expression was undetected in the hindbrain. (J:86221)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Camk2a     Summary of all recombinase alleles driven by Camk2a.
 

Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:86221 Schweizer C, et al., The gamma2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses. Mol Cell Neurosci. 2003 Oct;24(2):442-50
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/25/2015
MGI 5.21
The Jackson Laboratory