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Id3tm1Zhu
Targeted Allele Detail
Nomenclature
Symbol: Id3tm1Zhu
Name: inhibitor of DNA binding 3; targeted mutation 1, Yuan Zhuang
MGI ID: MGI:2679967
Synonyms: Id3-
Gene: Id3  Location: Chr4:136143822-136145392 bp, + strand  Genetic Position: Chr4, 68.34 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56950
Parent Cell Line:  AK7 (ES Cell)
Strain of Origin:  129S4/SvJaeSor
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe first 2 exons and part of exon 3 were replaced by a PGK neomycin cassette. Gene disruption was confirmed by Northern blot analysis. (J:56950)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Id3 Mutation:  11 strains or lines available
References
Original:  J:56950 Pan L, et al., Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene. Mol Cell Biol. 1999 Sep;19(9):5969-80
All:  54 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/05/2019
MGI 6.14
The Jackson Laboratory