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Targeted Allele Detail
Symbol: Rasgrf1tm3Pds
Name: RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 3, Paul D Soloway
MGI ID: MGI:2679658
Gene: Rasgrf1  Location: Chr9:89909908-90026977 bp, + strand  Genetic Position: Chr9, 47.31 cM
Germline Transmission:  Earliest citation of germline transmission: J:85825
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThis allele is based on the same vector as that used for Rasgrf1tm1Pds. In this case, the differentially methylated domain is replaced by both a floxed neomycin cassette and, immediately 3', the Igf2r region 2. (J:85825)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rasgrf1 Mutation:  35 strains or lines available
Original:  J:85825 Herman H, et al., Trans allele methylation and paramutation-like effects in mice. Nat Genet. 2003 Jun;34(2):199-202
All:  1 reference(s)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.11
The Jackson Laboratory