Rasgrf1^tm3Pds
Targeted Allele Detail

Summary

• Symbol: Rasgrf1^tm3Pds
• Name: RAS protein-specific guanine nucleotide-releasing factor 1; targeted mutation 3, Paul D Soloway
• MGI ID: MGI:2679658
• Gene: Rasgrf1 Location: Chr9:89791961-89909030 bp, + strand Genetic Position: Chr9, 47.31 cM
• Alliance: Rasgrf1^tm3Pds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:85825
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele is based on the same vector as that used for Rasgrf1^tm1Pds. In this case, the differentially methylated domain is replaced by both a floxed neomycin cassette and, immediately 3', the Igf2r region 2. (J:85825)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasgrf1 Mutation: 65 strains or lines available

References

• Original: J:85825 Herman H, et al., Trans allele methylation and paramutation-like effects in mice. Nat Genet. 2003 Jun;34(2):199-202
• All: 1 reference(s)