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Gene trapped Allele Detail
Symbol: Slit3Gt(OST106158)Lex
Name: slit guidance ligand 3; gene trap OST106158, Lexicon Genetics
MGI ID: MGI:2679499
Synonyms: Slit3Gt1Hhu
Gene: Slit3  Location: Chr11:35121456-35708507 bp, + strand  Genetic Position: Chr11, 20.29 cM, cytoband A5
Mutant Cell Line:  OST106158
Germline Transmission:  Earliest citation of germline transmission: J:86149
Parent Cell Line:  Lex-1 (ES Cell)
Strain of Origin:  129S5/SvEvBrd
Project Collection: Lexicon
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector
Mutation detailsThe endogenous locus was disrupted by gene trap mutation. RT-PCR analysis of homozygous mutant mice indicated transcript levels were reduced to less than 1.5% of those of wild-type mice. (J:86149)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
In Mice Carrying this Mutation: 14 assay results
In Structures Affected by this Mutation: 3 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Slit3 Mutation:  4 strains or lines available
See also, data as provided by Lexicon Genetics, Inc.
Original:  J:86149 Liu J, et al., Congenital diaphragmatic hernia, kidney agenesis and cardiac defects associated with Slit3-deficiency in mice. Mech Dev. 2003 Sep;120(9):1059-70
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory