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Arnttm1.2Gonz
Targeted Allele Detail
Nomenclature
Symbol: Arnttm1.2Gonz
Name: aryl hydrocarbon receptor nuclear translocator; targeted mutation 1.2, Frank Gonzalez
MGI ID: MGI:2679362
Synonyms: Arntdelta
Gene: Arnt  Location: Chr3:95434388-95497237 bp, + strand  Genetic Position: Chr3, 40.74 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:85934
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA single loxP site remained in place of exon 6 after the floxed region encompassing a neo cassette and exon 6 was excised from Arnttm1Gonz via cre mediated recombination in the germline. (J:85934)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arnt Mutation:  17 strains or lines available
References
Original:  J:85934 Tomita S, et al., T cell-specific disruption of arylhydrocarbon receptor nuclear translocator (Arnt) gene causes resistance to 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced thymic involution. J Immunol. 2003 Oct 15;171(8):4113-20
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/12/2015
MGI 5.21
The Jackson Laboratory