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QTL Variant Detail
QTL variant: Cara2C57BL/6J
Name: carcass ash in high growth mice 2; C57BL/6J
MGI ID: MGI:2678054
QTL: Cara2  Location: unknown  Genetic Position: Chr11, Syntenic
Strain of Specimen:  C57BL/6J
Allele Type:    QTL
Mutation:    Undefined
    This allele confers increased carcass ash weight compared to CAST/EiJ. (J:68441)
Inheritance:    Other (see notes)
View phenotypes and curated references for all genotypes (concatenated display).
Cara2 exhibits additive inheritance.

Mapping and Phenotype information for this QTL, its variants and associated markers


Authors indicated that enhanced growth rate in C57BL/6J-Cish2hg/Cish2hg mice may be modulated by other genes associated with growth. 1132 F2 mice from a cross between (C57BL/6J-Cish2hg/Cish2hg X CAST/EiJ)F1's yielded 274 +/+ , 596 hg/+ and 262 hg/hg mice with the hg/hg used in a genome wide scan to find QTLs associated with growth rates. A total of 15 QTLs were mapped. QTLs for total weight gain (wg1 - wg4) mapped to mouse Chromosomes 2, 8, and 11, with wg1 and wg2 mapping to mouse chromosome 2.QTLS for total carcass protein (Carp1-Carp3) mapped to Chromosomes 2, 11 and 17. QTLs for total carcass ash weight (Cara1-Cara3) mapped to mouse Chromosomes 2, 11 and 17. QTLs for percent carcass fat (Carf1 and Carf2) mapped to mouse Chromosomes 5 and 9 and QTLS for femur length (Feml1-Feml3) mapped to mouse chromosomes 2, 9, and 17.

Original:  J:68441 Corva PM, et al., Quantitative trait loci affecting growth in high growth (hg) mice. Mamm Genome. 2001 Apr;12(4):284-90
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
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