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Hba-a1tm1Ywk
Targeted Allele Detail
Nomenclature
Symbol: Hba-a1tm1Ywk
Name: hemoglobin alpha, adult chain 1; targeted mutation 1, Yuet Wai Kan
MGI ID: MGI:2677594
Synonyms: *alpha
Gene: Hba-a1  Location: Chr11:32283511-32284465 bp, + strand  Genetic Position: Chr11, 18.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35018
Parent Cell Line:  JM-1 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    A neomycin selection cassette replaced part of the second exon of the gene. (J:35018)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hba-a1 Mutation:  1 strain or line available
References
Original:  J:35018 Chang J, et al., Inactivation of mouse alpha-globin gene by homologous recombination: mouse model of hemoglobin H disease. Blood. 1996 Sep 1;88(5):1846-51
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/21/2014
MGI 5.20
The Jackson Laboratory