Igf2^tm1Kel
Targeted Allele Detail

Summary

• Symbol: Igf2^tm1Kel
• Name: insulin-like growth factor 2; targeted mutation 1, Gavin Derek Kelsey
• MGI ID: MGI:2677154
• Synonyms: Igf2^tm1Kel-pat
• Gene: Igf2 Location: Chr7:142204503-142220553 bp, - strand Genetic Position: Chr7, 87.99 cM
• Alliance: Igf2^tm1Kel page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:65001
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: Exon 4 was disrupted by the insertion of a cassette containing IRES-lacZ and a neomycin resistance gene. Neither transcript nor protein was reported to be expressed from this allele. (J:65001)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igf2 Mutation: 25 strains or lines available

References

• Original: J:65001 Constancia M, et al., Deletion of a silencer element in igf2 results in loss of imprinting independent of H19. Nat Genet. 2000 Oct;26(2):203-6
• All: 3 reference(s)