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Pkd2tm1Dwo
Targeted Allele Detail
Nomenclature
Symbol: Pkd2tm1Dwo
Name: polycystic kidney disease 2; targeted mutation 1, Bernd Dworniczak
MGI ID: MGI:2676373
Synonyms: Pkd2-/-lacZ+/+, Pkd2tm1Blum
Gene: Pkd2  Location: Chr5:104459450-104505819 bp, + strand  Genetic Position: Chr5, 50.68 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77401
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pkd2 Mutation:  22 strains or lines available
References
Original:  J:77401 Pennekamp P, et al., The ion channel polycystin-2 is required for left-right axis determination in mice. Curr Biol. 2002 Jun 4;12(11):938-43
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/12/2014
MGI 5.19
The Jackson Laboratory