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Mpgtm1Lds
Targeted Allele Detail
Nomenclature
Symbol: Mpgtm1Lds
Name: N-methylpurine-DNA glycosylase; targeted mutation 1, Leona D Samson
MGI ID: MGI:2675730
Synonyms: Aag -
Gene: Mpg  Location: Chr11:32226505-32232700 bp, + strand  Genetic Position: Chr11, 18.83 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77298
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA neomycin resistance cassette was inserted into exon 2. Cells derived from homozygous mice have no detectable gene transcripts or 3MeA DNA glycosylase activity. (J:31763)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mpg Mutation:  11 strains or lines available
References
Original:  J:77298 Engelward BP, et al., Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13087-92
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory