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Cd69tm1Naka
Targeted Allele Detail
Nomenclature
Symbol: Cd69tm1Naka
Name: CD69 antigen; targeted mutation 1, Toshinori Nakayama
MGI ID: MGI:2675144
Gene: Cd69  Location: Chr6:129267325-129275436 bp, - strand  Genetic Position: Chr6, 63.21 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84940
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin selection cassette inserted by homologous recombination. Protein was undetected by flow cytometric analysis of activated T cells obtained from homozygous mutant mice. (J:84940)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd69 Mutation:  9 strains or lines available
References
Original:  J:84940 Murata K, et al., CD69-null mice protected from arthritis induced with anti-type II collagen antibodies. Int Immunol. 2003 Aug;15(8):987-92
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/14/2017
MGI 6.08
The Jackson Laboratory