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Meox1tm1Bmk
Targeted Allele Detail
Nomenclature
Symbol: Meox1tm1Bmk
Name: mesenchyme homeobox 1; targeted mutation 1, Baljinder S Mankoo
MGI ID: MGI:2674273
Synonyms: Meox1-, Meox1tm1BSM
Gene: Meox1  Location: Chr11:101877510-101894354 bp, - strand  Genetic Position: Chr11, 65.48 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84754
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExon 1, which includes the start codon, and 2.3 kb of upstream intronic sequence was deleted by homologous recombination of a targeting vector. Transcript was reported to be undetected in homozygous mutant mice. (J:84754)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Meox1 Mutation:  11 strains or lines available
References
Original:  J:84754 Mankoo BS, et al., The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites. Development. 2003 Oct;130(19):4655-64
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory