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Targeted Allele Detail
Symbol: Serpinb6atm1.1Pib
Name: serine (or cysteine) peptidase inhibitor, clade B, member 6a; targeted mutation 1.1, Phillip I Bird
MGI ID: MGI:2673997
Gene: Serpinb6a  Location: Chr13:33917918-34002794 bp, - strand  Genetic Position: Chr13, 14.0 cM
Germline Transmission:  Earliest citation of germline transmission: J:85039
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe floxed neo cassette immediately downstrean of EGFP was excised from Serpinb6atm1Pib via cre mediated recombination in vitro. Expression of GFP recapitulated endogenous expression. Western blot analysis indicated an absence of normal protein in homozygous mutant spleen and thymus tissue. (J:85039)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpinb6a Mutation:  4 strains or lines available
Original:  J:85039 Scarff KL, et al., A retained selection cassette increases reporter gene expression without affecting tissue distribution in SPI3 knockout/GFP knock-in mice. Genesis. 2003 Jul;36(3):149-57
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory