Slc4a1^l11Jus51
Chemically induced Allele Detail

Summary

• Symbol: Slc4a1^l11Jus51
• Name: solute carrier family 4 (anion exchanger), member 1; lethal, Chr 11, Justice 51
• MGI ID: MGI:2671922
• Synonyms: l11Jus51
• Gene: Slc4a1 Location: Chr11:102239646-102256107 bp, - strand Genetic Position: Chr11, 66.29 cM, cytoband D
• Alliance: Slc4a1^l11Jus51 page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Mutagenesis for Dev. Defects

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen at the Baylor College of Medicine. It failed to complement the existing mutation Slc4a1^tm1Llp. The mutation was identified as an A-to-T transversion resulting in a missense mutation in the codon corresponding to amino acid 541. This conserved glutamic acid within the fifth transmembrane domain is changed to a valine in the encoded protein. (J:85113)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc4a1 Mutation: 54 strains or lines available

References

• Original: J:85113 Kile BT, et al., Functional genetic analysis of mouse chromosome 11. Nature. 2003 Sep 4;425(6953):81-6
• All: 3 reference(s)