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Rdxtm1Sts
Targeted Allele Detail
Nomenclature
Symbol: Rdxtm1Sts
Name: radixin; targeted mutation 1, Shoichiro Tsukita
MGI ID: MGI:2671151
Synonyms: Rdx-
Gene: Rdx  Location: Chr9:52047150-52088737 bp, + strand  Genetic Position: Chr9, 28.62 cM
Stereocilia abnormalities on Rdxtm1Sts/Rdxtm1Sts cochlear hair cells of adult and newborn mice

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:77485
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rdx Mutation:  15 strains or lines available
References
Original:  J:77485 Kikuchi S, et al., Radixin deficiency causes conjugated hyperbilirubinemia with loss of Mrp2 from bile canalicular membranes. Nat Genet. 2002 Jul;31(3):320-5
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory