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Targeted Allele Detail
Symbol: Kcnip2tm1Krc
Name: Kv channel-interacting protein 2; targeted mutation 1, Kenneth R Chien
MGI ID: MGI:2671134
Synonyms: KChIP2-
Gene: Kcnip2  Location: Chr19:45792346-45816422 bp, - strand  Genetic Position: Chr19, 38.75 cM, cytoband D1
Germline Transmission:  Earliest citation of germline transmission: J:76843
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA neomycin selection cassette replaced a genomic fragment of the gene that contained exons 4 though 9. Morthern blot analysis of RNA derived from homozygous mice demonstrated that no detectable transcript was expressed from this allele. (J:76843)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnip2 Mutation:  5 strains or lines available
Original:  J:76843 Kuo HC, et al., A defect in the Kv channel-interacting protein 2 (KChIP2) gene leads to a complete loss of I(to) and confers susceptibility to ventricular tachycardia. Cell. 2001 Dec 14;107(6):801-13
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.16
The Jackson Laboratory