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Ubash3btm1Jni
Targeted Allele Detail
Nomenclature
Symbol: Ubash3btm1Jni
Name: ubiquitin associated and SH3 domain containing, B; targeted mutation 1, James N Ihle
MGI ID: MGI:2670555
Synonyms: Elf1tm1Jni, p70 deficient, Sts1-
Gene: Ubash3b  Location: Chr9:41011098-41161697 bp, - strand  Genetic Position: Chr9, 21.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:79606
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 2 and 3 were replaced with a neomycin resistance gene in the antisensense orientation. Northern blot analysis indicated a lack of transcript while the absence of protein was confirmed immunologically. (J:79606)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ubash3b Mutation:  28 strains or lines available
References
Original:  J:79606 Carpino N, et al., Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein. Mol Cell Biol. 2002 Nov;22(21):7491-500
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/11/2018
MGI 6.12
The Jackson Laboratory