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Targeted Allele Detail
Symbol: Rab3dtm1Rja
Name: RAB3D, member RAS oncogene family; targeted mutation 1, Reinhard Jahn
MGI ID: MGI:2669989
Synonyms: Rab3D-KO
Gene: Rab3d  Location: Chr9:21907491-21918183 bp, - strand  Genetic Position: Chr9, 7.91 cM, cytoband A2-A3
Germline Transmission:  Earliest citation of germline transmission: J:84542
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe first exon was replaced with a neomycin resistance gene. Absence of gene protein was established by immunoblot analysis of pancreatic zymogen granules from homozygous mice. (J:84542)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rab3d Mutation:  8 strains or lines available
Original:  J:84542 Riedel D, et al., Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules. Mol Cell Biol. 2002 Sep;22(18):6487-97
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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MGI 6.13
The Jackson Laboratory