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Gt(ROSA)26Sortm1(cre/ERT)Nat
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm1(cre/ERT)Nat
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jeremy Nathans
MGI ID: MGI:2669525
Synonyms: CreERT1, Gt(ROSA)26Sortm1(cre/Esr1)Nat, R26CreER, R26ERCre, R26RNatCre
Gene: Gt(ROSA)26Sor  Location: Chr6:113067428-113077333 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84747
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    induced by tamoxifen
Mutation:    Insertion
 
Mutation details
Inheritance:    Dominant
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gt(ROSA)26Sor     Summary of all recombinase alleles driven by Gt(ROSA)26Sor.
 

Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  243 strains or lines available
References
Original:  J:84747 Badea TC, et al., A noninvasive genetic/pharmacologic strategy for visualizing cell morphology and clonal relationships in the mouse. J Neurosci. 2003 Mar 15;23(6):2314-22
All:  68 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory