About   Help   FAQ
The MGI survey is now closed.
Thanks for your support!
Prkg1tm2Naw
Targeted Allele Detail
Nomenclature
Symbol: Prkg1tm2Naw
Name: protein kinase, cGMP-dependent, type I; targeted mutation 2, Hermann Nawrath
MGI ID: MGI:2668652
Synonyms: CGKIL2
Gene: Prkg1  Location: Chr19:30567551-31765033 bp, - strand  Genetic Position: Chr19, 25.17 cM, cytoband C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84611
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 10 was left flanked by loxP sites after the homologous recombination of a targeting vector containing a single loxP site upstream of exon 10 and tk-neo cassette with a 3' loxP site in intron 10. (J:84611)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkg1 Mutation:  13 strains or lines available
References
Original:  J:84611 Wegener JW, et al., cGMP-dependent protein kinase I mediates the negative inotropic effect of cGMP in the murine myocardium. Circ Res. 2002 Jan 11;90(1):18-20
All:  11 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/20/2015
MGI 5.21
The Jackson Laboratory