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Mgat2tm1.1Jxm
Targeted Allele Detail
Nomenclature
Symbol: Mgat2tm1.1Jxm
Name: mannoside acetylglucosaminyltransferase 2; targeted mutation 1.1, Jamey Marth
MGI ID: MGI:2667740
Synonyms: Mgat2delta
Gene: Mgat2  Location: Chr12:69184157-69186770 bp, + strand  Genetic Position: Chr12, 28.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80661
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region, which is contained within a single exon, was deleted when the flanking loxP sites present in Mgat2tm1Jxm were recombined in the germline. (J:80661)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 12 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mgat2 Mutation:  9 strains or lines available
References
Original:  J:80661 Wang Y, et al., Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Glycobiology. 2001 Dec;11(12):1051-70
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/03/2020
MGI 6.15
The Jackson Laboratory