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Mgat2tm1Jxm
Targeted Allele Detail
Nomenclature
Symbol: Mgat2tm1Jxm
Name: mannoside acetylglucosaminyltransferase 2; targeted mutation 1, Jamey Marth
MGI ID: MGI:2667720
Synonyms: Mgat2F
Gene: Mgat2  Location: Chr12:69230931-69233544 bp, + strand  Genetic Position: Chr12, 28.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:80661
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe single coding exon of the endogenous locus was flanked by intronic loxP sites inserted by homologous recombination. (J:80661)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mgat2 Mutation:  9 strains or lines available
References
Original:  J:80661 Wang Y, et al., Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Glycobiology. 2001 Dec;11(12):1051-70
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory