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Slc27a4tm1.1Wsr
Targeted Allele Detail
Nomenclature
Symbol: Slc27a4tm1.1Wsr
Name: solute carrier family 27 (fatty acid transporter), member 4; targeted mutation 1.1, Wolfgang Stremmel
MGI ID: MGI:2667329
Synonyms: Fatp4-/-, Fatp4deltaEx3, Fatp4-KO
Gene: Slc27a4  Location: Chr2:29802634-29817522 bp, + strand  Genetic Position: Chr2, 20.64 cM, cytoband B
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:84096
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele was generated from Slc27a4tm1Wsr by crossing mutant mice with mice transgenic for PGK-Cre. This resulted in the excision of exon 3 as a result of the ubiquitously expressed Cre activity. Northern blot and Western blot analyses demonstrated the absence of transcripts and protein products. (J:84096)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc27a4 Mutation:  17 strains or lines available
References
Original:  J:84096 Herrmann T, et al., Mice with targeted disruption of the fatty acid transport protein 4 (Fatp 4, Slc27a4) gene show features of lethal restrictive dermopathy. J Cell Biol. 2003 Jun 23;161(6):1105-15
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory