About   Help   FAQ
Nsd1tm1.1Pcn
Targeted Allele Detail
Nomenclature
Symbol: Nsd1tm1.1Pcn
Name: nuclear receptor-binding SET-domain protein 1; targeted mutation 1.1, Pierre Chambon
MGI ID: MGI:2667262
Synonyms: NSD1-
Gene: Nsd1  Location: Chr13:55209782-55318325 bp, + strand  Genetic Position: Chr13, 29.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83923
Parent Cell Line:  P1 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThis allele was generated by crossing mice heterozygous for Nsd1tm1Pcn with cytomegalovirus-Cre mice which express the Cre recombinase in the germline. Animals in which Cre-mediated excision of the neomycin gene and exon 2 occurred were detected by PCR analysis. (J:83923)
Phenotypes
Loading...
View phenotypes for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nsd1 Mutation:  224 strains or lines available
References
Original:  J:83923 Rayasam GV, et al., NSD1 is essential for early post-implantation development and has a catalytically active SET domain. EMBO J. 2003 Jun 16;22(12):3153-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/25/2015
MGI 5.21
The Jackson Laboratory