About   Help   FAQ
Tg(Myh6-tTA)6Smbf
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-tTA)6Smbf
Name: transgene insertion 6, Section of Myocardial Biology - Fishman Lab
MGI ID: MGI:2665551
Synonyms: 2.9alphatTA, alphaMHC-tTA, alphaMtTA, Tg(MHCAtTA)6Smbf
Transgene: Tg(Myh6-tTA)6Smbf  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe transgene consists of a rat Myh6 promoter and a tetracycline transactivator sequence. Transgene expression in cardiac tissue was confirmed by Northern blot analysis. 2.9 kb of rat Myh6 promoter sequences directs transgene expression in the heart starting at embryonic day E7.5. (J:82692)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Notes
Transgenic line 6 showed the strongest cardiac transgene expression and was used for analysis.
References
Original:  J:82692 Yu Z, et al., Conditional transgene expression in the heart. Circ Res. 1996 Oct;79(4):691-7
All:  68 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
12/03/2019
MGI 6.14
The Jackson Laboratory