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Mafftm1.1Jeng
Targeted Allele Detail
Summary
Symbol: Mafftm1.1Jeng
Name: v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian); targeted mutation 1.1, James Douglas Engel
MGI ID: MGI:2663639
Gene: Maff  Location: Chr15:79230821-79243276 bp, + strand  Genetic Position: Chr15, 37.7 cM
Alliance: Mafftm1.1Jeng page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:56405
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAs in Mafftm1Jeng, the entire coding region, except for the first 3 codons, was replaced with a cassette containing lacZ and a floxed selection region. Prior to implantation and germline transmission, the floxed region was excised via cre mediated recombination, leaving lacZ intact. (J:56405)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Maff Mutation:  8 strains or lines available
References
Original:  J:56405 Onodera K, et al., Characterization of the murine mafF gene. J Biol Chem. 1999 Jul 23;274(30):21162-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory