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Lrp4mdig
Spontaneous Allele Detail
Nomenclature
Symbol: Lrp4mdig
Name: low density lipoprotein receptor-related protein 4; malformed digits
MGI ID: MGI:2661383
Gene: Lrp4  Location: Chr2:91457511-91513779 bp, + strand  Genetic Position: Chr2, 50.63 cM
Lrp4mdig/Lrp4mdig with control

Show the 2 phenotype image(s) involving this allele.

Mutation
origin
Strain of Origin:  DBA/1LacJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsAn A to T transversion at the 3' end of exon 15 results in a mutant splice site. As a consequence, exon 15 is skipped. (J:108168)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 assay results
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lrp4 Mutation:  8 strains or lines available
References
Original:  J:83757 Cook SA, et al., A new mutation, mdig, in the Fnbp4-Alx4-Ext2 region of mouse Chromosome 2. Mouse Mutant Resources Web Site, The Jackson Laboratory, Bar Harbor, Maine. MGI Direct Data Submission. 2003;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory