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Mpltm1Mwm
Targeted Allele Detail
Nomenclature
Symbol: Mpltm1Mwm
Name: myeloproliferative leukemia virus oncogene; targeted mutation 1, Mark W Moore
MGI ID: MGI:2660810
Synonyms: c-mpl -
Gene: Mpl  Location: Chr4:118442415-118457513 bp, - strand  Genetic Position: Chr4, 54.61 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:83264
Parent Cell Line:  D3 (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin selection cassette was inserted into exon 3. (J:83264)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mpl Mutation:  2 strains or lines available
References
Original:  J:83264 Gurney AL, et al., Thrombocytopenia in c-mpl-deficient mice. Science. 1994 Sep 2;265(5177):1445-7
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory