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Tg(Pgr)3Shy
Transgene Detail
Nomenclature
Symbol: Tg(Pgr)3Shy
Name: transgene insertion 3, G Shyamala
MGI ID: MGI:2657219
Transgene: Tg(Pgr)3Shy  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Pgr)3Shy expresses 1 gene
 
Mutation detailsA mouse Pgr cDNA preceded by 4 GAL4 binding sites was used for the transgene. The Pgr sequence encodes the B isoform of Pgr and includes intron 1. A mutation was engineered into the second ATG. (J:83103)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Bigenic founder mice (containing the GAL4 driver and Pgr B isoform transgenes) were created.
References
Original:  J:83103 Shyamala G, et al., Impact of progesterone receptor on cell-fate decisions during mammary gland development. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3044-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory