Ctnnb1^Bfc
Chemically induced Allele Detail

Summary

• Symbol: Ctnnb1^Bfc
• Name: catenin beta 1; batface
• MGI ID: MGI:2656734
• Synonyms: Gena123, GENA 123
• Gene: Ctnnb1 Location: Chr9:120762466-120789573 bp, + strand Genetic Position: Chr9, 72.19 cM
• Alliance: Ctnnb1^Bfc page

Mutation origin

• Strain of Origin: (C3H/HeNCrl x BALB/cAnNCrl)F1
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a C to A transversion that results in the amino acid substitution of lysine for threonine at position 653 (T653K). (J:170646)
• Inheritance: Dominant

Expression

In Mice Carrying this Mutation:	2 assay results
In Structures Affected by this Mutation:	13 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Ctnnb1 Mutation: 49 strains or lines available

References

• Original: J:63816 Nolan PM, et al., A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat Genet. 2000 Aug;25(4):440-3
• All: 8 reference(s)