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Rnaseh1tm1Crh
Targeted Allele Detail
Nomenclature
Symbol: Rnaseh1tm1Crh
Name: ribonuclease H1; targeted mutation 1, Robert J Crouch
MGI ID: MGI:2655784
Synonyms: Rnaseh1
Gene: Rnaseh1  Location: Chr12:28649602-28659589 bp, + strand  Genetic Position: Chr12, 10.99 cM, cytoband A3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82764
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exons 2-4 with a PGK-neo cassette via homologous recombination. (J:82764)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rnaseh1 Mutation:  30 strains or lines available
References
Original:  J:82764 Cerritelli SM, et al., Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice. Mol Cell. 2003 Mar;11(3):807-15
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory