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St3gal5tm1Rlp
Targeted Allele Detail
Nomenclature
Symbol: St3gal5tm1Rlp
Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 5; targeted mutation 1, Richard L Proia
MGI ID: MGI:2655771
Synonyms: GM3S-, Siat9-
Gene: St3gal5  Location: Chr6:72074576-72131555 bp, + strand  Genetic Position: Chr6, 32.24 cM, cytoband C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82723
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 4 was replaced with a neomycin selection cassette inserted by homologous recombination. Transcript was undetected by Northern blot analysis of brain RNA obtained from homozygous mutant mice. (J:82723)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any St3gal5 Mutation:  15 strains or lines available
References
Original:  J:82723 Yamashita T, et al., Enhanced insulin sensitivity in mice lacking ganglioside GM3. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3445-9
All:  20 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/12/2022
MGI 6.17
The Jackson Laboratory