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Cd40tm1Geha
Targeted Allele Detail
Nomenclature
Symbol: Cd40tm1Geha
Name: CD40 antigen; targeted mutation 1, Raif S Geha
MGI ID: MGI:2655321
Synonyms: CD40-, CD40M
Gene: Cd40  Location: Chr2:165055627-165072948 bp, + strand  Genetic Position: Chr2, 85.38 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82369
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe gene was disrupted by replacement of exons 7, 8, and 9 with a neomycin resistance cassette via homologous recombination. (J:82369)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd40 Mutation:  13 strains or lines available
References
Original:  J:82369 Castigli E, et al., CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):12135-9
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory