Ifnar1^tm1Uka
Targeted Allele Detail

Summary

• Symbol: Ifnar1^tm1Uka
• Name: interferon (alpha and beta) receptor 1; targeted mutation 1, Ulrich Kalinke
• MGI ID: MGI:2655303
• Synonyms: Ifnar1^F, IFNAR1^fl
• Gene: Ifnar1 Location: Chr16:91282126-91304329 bp, + strand Genetic Position: Chr16, 52.98 cM
• Alliance: Ifnar1^tm1Uka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: IB10/E14IB10 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 10 of the gene locus was flanked by loxP sites. Upon cre-mediated deletion, a frameshift mutation results in disruption of the transmembrane region and cytoplasmic signaling domain. (J:82809, J:129128)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifnar1 Mutation: 59 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 62 reference(s)