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Ifnar1tm1Uka
Targeted Allele Detail
Nomenclature
Symbol: Ifnar1tm1Uka
Name: interferon (alpha and beta) receptor 1; targeted mutation 1, Ulrich Kalinke
MGI ID: MGI:2655303
Synonyms: Ifnar1F, IFNAR1fl
Gene: Ifnar1  Location: Chr16:91485238-91507441 bp, + strand  Genetic Position: Chr16, 52.98 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  IB10/E14IB10 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 10 of the gene locus was flanked by loxP sites. Upon cre-mediated deletion, a frameshift mutation results in disruption of the transmembrane region and cytoplasmic signaling domain. (J:82809, J:129128)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ifnar1 Mutation:  33 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  38 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory