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Hoxb13tm2Mrc
Targeted Allele Detail
Nomenclature
Symbol: Hoxb13tm2Mrc
Name: homeobox B13; targeted mutation 2, Mario R Capecchi
MGI ID: MGI:2655242
Synonyms: Hoxb13lxp
Gene: Hoxb13  Location: Chr11:96194316-96197447 bp, + strand  Genetic Position: Chr11, 59.63 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82540
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loss of function allele was generated by cre mediated excision of the floxed neo cassette from Hoxb13tm4Mrc. A single loxP site remained in place of codon 33. (J:82540, J:82849)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxb13 Mutation:  6 strains or lines available
References
Original:  J:82540 Economides KD, et al., Hoxb13 is required for normal differentiation and secretory function of the ventral prostate. Development. 2003 May;130(10):2061-9
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory