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Thratm2Ven
Targeted Allele Detail
Nomenclature
Symbol: Thratm2Ven
Name: thyroid hormone receptor alpha; targeted mutation 2, Bjorn Vennstrom
MGI ID: MGI:2654864
Synonyms: alphatm2, TRalpha2 -
Gene: Thra  Location: Chr11:98740638-98769006 bp, + strand  Genetic Position: Chr11, 62.58 cM, cytoband D-E
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72959
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Thra Mutation:  17 strains or lines available
References
Original:  J:72959 Salto C, et al., Ablation of TRalpha2 and a Concomitant Overexpression of alpha1 Yields a Mixed Hypo- and Hyperthyroid Phenotype in Mice. Mol Endocrinol. 2001 Dec;15(12):2115-28
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory