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Tg(KRT5-cre/PGR)1Der
Transgene Detail
Nomenclature
Symbol: Tg(KRT5-cre/PGR)1Der
Name: transgene insertion 1, Dennis R Roop
MGI ID: MGI:2651408
Synonyms: K5-Cre, K5-CrePR, K5CrePR1, K5.CrePR1
Transgene: Tg(KRT5-cre/PGR)1Der  Location: unknown  
Transgene
origin
Strain of Origin:  (ICR x FVB)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    mifepristone
Mutation:    Insertion
 
Mutation detailsThis transgene expresses a Cre recombinase and human progesterone receptor gene fusion under the control of a bovine keratin 5 promoter, active in the basal layer of the epidermis and hair follicles. (J:75280)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: KRT5     Summary of all recombinase alleles driven by KRT5.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:75280 Zhou Z, et al., In utero activation of K5.CrePR1 induces gene deletion. Genesis. 2002 Feb;32(2):191-2
All:  22 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/09/2019
MGI 6.14
The Jackson Laboratory