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Atxn7tm1Hzo
Targeted Allele Detail
Nomenclature
Symbol: Atxn7tm1Hzo
Name: ataxin 7; targeted mutation 1, Huda Y Zoghbi
MGI ID: MGI:2651378
Synonyms: Sca7266Q, Sca7266Q/5Q
Gene: Atxn7  Location: Chr14:14012491-14107296 bp, + strand  Genetic Position: Chr14, 7.08 cM
Altered rod photoreceptor nuclear architecture in Tg(RHO-SCA7)R7EJman/0 and Atxn7tm1Hzo/Atxn7+ mice, but not in Tg(RHO-SCA7)R7NJman/0 mice

Show the 1 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82072
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted
Mutation:    Insertion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Atxn7 Mutation:  7 strains or lines available
References
Original:  J:82072 Yoo SY, et al., SCA7 knockin mice model human SCA7 and reveal gradual accumulation of mutant ataxin-7 in neurons and abnormalities in short-term plasticity. Neuron. 2003 Feb 6;37(3):383-401
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory