Egr4tm1Jmi
Targeted Allele Detail
|
Symbol: |
Egr4tm1Jmi |
Name: |
early growth response 4; targeted mutation 1, Jeffrey Milbrandt |
MGI ID: |
MGI:2450146 |
Gene: |
Egr4 Location: Chr6:85488103-85490571 bp, - strand Genetic Position: Chr6, 37.48 cM
|
Alliance: |
Egr4tm1Jmi page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:58099
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
Not Specified
|
|
Allele Type: |
|
Targeted (Null/knockout) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: The insertion of a neomycin selection cassette deleted a portion of the zinc finger binding domain and precluded the translation of downstream amino acids. While normal transcript was undetected by Northern blot analysis of homozygous mutant brain and testis tissue, low levels of a transcript encoding 5' amino acids and a portion of neo was observed.
(J:58099)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Egr4 Mutation: |
13 strains or lines available
|
|
Original: |
J:58099 Tourtellotte WG, et al., Infertility associated with incomplete spermatogenic arrest and oligozoospermia in Egr4-deficient mice. Development. 1999 Nov;126(22):5061-71 |
All: |
4 reference(s) |
|