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Tg(KRT14-Pgf)1Odo
Transgene Detail
Nomenclature
Symbol: Tg(KRT14-Pgf)1Odo
Name: transgene insertion 1, Teresa Odorisio
MGI ID: MGI:2450137
Synonyms: K14-PlGF
Transgene: Tg(KRT14-Pgf)1Odo  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(KRT14-Pgf)1Odo expresses 1 gene
 
Mutation detailsThe human KRT14 promoter was used to overexpress the mouse PGF (nucleotides 119-595) in skin cells. Expression of the transgene in epidermal cells was confirmed by in situ hybridization analysis of skin sections, and by Western blot analysis of skin lysates. (J:77722)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
The 2 highest expressing transgenic lines, carrying 10-12 copies of the transgene, were used for analysis.
References
Original:  J:77722 Odorisio T, et al., Mice overexpressing placenta growth factor exhibit increased vascularization and vessel permeability. J Cell Sci. 2002 Jun 15;115(Pt 12):2559-67
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory