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Btktm1Gsv
Targeted Allele Detail
Nomenclature
Symbol: Btktm1Gsv
Name: Bruton agammaglobulinemia tyrosine kinase; targeted mutation 1, Frank Grosveld
MGI ID: MGI:2449487
Synonyms: Btk-
Gene: Btk  Location: ChrX:134542336-134583570 bp, - strand  Genetic Position: ChrX, 56.18 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:35769
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Btk Mutation:  11 strains or lines available
References
Original:  J:35769 Hendriks RW, et al., Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage. EMBO J. 1996 Sep 16;15(18):4862-72
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory