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Tg(TIE2-lacZ)182Sato
Transgene Detail
Nomenclature
Symbol: Tg(TIE2-lacZ)182Sato
Name: transgene insertion 182, Thomas N Sato
MGI ID: MGI:2449204
Synonyms: Tg182Sato, Tg(TIE2LacZ)182Sato, Tie2-lacZ, Tie2/LacZ, TIE2p/e-LacZ
Transgene: Tg(TIE2-lacZ)182Sato  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene consists of a mouse Tek promoter and enhancer element, a lacZ reporter gene, and an SV40 polyadenylation sequence. The enhancer element is a genomic fragment extending from 3' of exon 1 to 10 kb into intron 1. Expression was driven in endothelial cells. (J:39276)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Notes
In embryonic and adult transgenic mice on an FVB/N background, LacZ is expressed specifically in vascular endothelial cells.
References
Original:  J:39276 Schlaeger TM, et al., Uniform vascular-endothelial-cell-specific gene expression in both embryonic and adult transgenic mice. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3058-63
All:  45 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/15/2020
MGI 6.15
The Jackson Laboratory